Join Bristol Myers Squibb: Life-Changing Career Opportunities

Challenging. Meaningful. Life-changing. At Bristol Myers Squibb, these aren’t just words; they define our work environment. Our unique and transformative projects span every department, from optimizing production lines to breakthrough advancements in cell therapy. By joining us, you'll have the opportunity to make a significant impact on patients’ lives while advancing your career in ways you never imagined.

Why Work with Us?

At Bristol Myers Squibb, we recognize the importance of balance and flexibility in the workplace. We offer a comprehensive range of competitive benefits, services, and programs designed to support our employees' professional and personal growth. For more information, visit .

Our Mission: Informatics and Predictive Sciences (IPS)

Join a diverse, high-achieving team dedicated to pioneering transformative insights for patient benefit. Our IPS team conducts advanced computational research across genomics, structural and molecular informatics, computational and systems biology, patient selection, translational biomarker research, knowledge science, epidemiology, and machine learning.

We collaborate closely with scientific and clinical experts to drive innovative science and make data-driven decisions, contributing to our rich pipeline of next-generation medicines.

The Role: Principal Scientist, Machine Learning/Predictive Cell State Design

We are seeking a Principal Scientist to join our computational research group within the global IPS organization. Collaborating with Cancer Immunology & Cell Therapy Thematic Research Center (CICT TRC) colleagues, you will optimize cell therapies, identify molecular mechanisms to enhance efficacy, and reduce potential toxicities.

Key Responsibilities

• Develop large multimodal models integrating structured and unstructured data for cell engineering and target discovery applications.
• Develop ML-based methodologies for spatial transcriptomics datasets to enhance cancer immunology drug discovery.
• Utilize ML and causal inference techniques to predict perturbation effects on cell states and phenotypes.
• Stay updated on state-of-the-art ML methodologies and their applications in cell engineering and drug discovery.
• Collaborate with cross-functional teams to design experiments and translate computational insights into therapeutic concepts.
• Contribute to the authorship of scientific reports and present methods and conclusions to publishable standards.

Basic Qualifications

Applicants must have one of the following academic and professional experiences:

• Bachelor's degree with 8+ years of experience.
• Master's degree with 6+ years of experience.
• PhD with 4+ years of experience.

Preferred Qualifications

• PhD in computer science, computational biology, bioinformatics, biomedical informatics, genetics, statistics, or a related field with a strong publication record.
• Experience in developing and implementing scalable machine learning architectures for large multi-modal datasets.
• Expertise in Python, PyTorch, and open-source data processing and visualization packages.
• Experience with deep learning methodologies and cloud computing services.
• Proven problem-solving skills and collaborative nature.
• Familiarity with cell biology, immunology, oncology, or biologics is a plus.
• Fluent in verbal and written English.

Our Commitment to Diversity and Inclusion

At Bristol Myers Squibb, we are passionate about making a positive impact on patients with serious diseases. We strive to create an inclusive culture where our shared values of passion, innovation, urgency, accountability, inclusion, and integrity bring out the best in each of us. If this role aligns with your aspirations, we encourage you to apply, even if your experience doesn't match perfectly.

Workplace Flexibility and On-site Protocol

We have a flexible work structure that includes site-essential, site-by-design, field-based, and remote-by-design roles. Depending on your role, you may be required to work onsite part or full-time. We also provide reasonable accommodations for employees with disabilities to ensure support in their roles. For more information, visit our Equal Employment Opportunity statement at .

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