Join AstraZeneca as a Senior Clinical Data Manager in Toronto

At AstraZeneca, we pride ourselves on fostering a collaborative culture that emphasizes knowledge-sharing, ambitious thinking, and innovation. Our global teams work together to push boundaries and achieve extraordinary results.

Why Work With Us?

Our Toronto head office and BlueSky Hub are purposefully designed to enhance teamwork and creativity. We value individualized flexibility, allowing employees to balance personal and work commitments. To ensure a strong culture of collaboration, we engage face-to-face in our offices three days a week.

Sustainability is central to our culture. We know that the health of people, the planet, and our business are interconnected. Therefore, we are committed to tackling major challenges such as climate change, healthcare access, and disease prevention.

Role and Responsibilities

As a Senior Clinical Data Manager, you will be responsible for coordinating Clinical Data Management (CDM) deliverables on assigned clinical studies. You might act as a core member of the Global Study Team (GST) and lead studies with lesser complexities. Your role will include:

• Coordinating CDM deliverables based on the relevant model and DM Vendor.
• Providing leadership and operational knowledge in planning and delivering CDM at a study level, potentially under the mentorship of a Principal Project Data Manager.
• Communicating and collaborating effectively with all study level team members.
• Serving as the primary point of contact for DM vendors and providing guidance and supervision to Lead Data Managers/DM Team Leads.
• Overseeing the daily operational aspects of CDM for assigned studies, identifying risks, and collaborating with DM Vendors to mitigate these risks.
• Understanding therapeutic area, indication, or program-specific data capture standards and AstraZeneca standards.
• Providing input into CDM activities associated with regulatory inspections/audits for assigned studies.
• Ensuring compliance with Trial Master File requirements related to DM Vendors.
• Supporting Senior Leaders to oversee CDM Vendor performance, including reviewing and managing DM Vendor delivery against KPIs, budget, and overall performance.
• Driving adherence to AstraZeneca CDM standards and processes for data quality and consistency.
• Mentoring junior Clinical Data Management colleagues.
• Handling any CDM-related ad-hoc requests from Line Manager or senior management.

Education, Qualifications, Skills, and Experience

We are looking for candidates with the following qualifications:

• University or college degree in life sciences, pharmacy, nursing, or a related field.
• Knowledge of Clinical Data Management and experience in the Biotech/Pharma/CRO industry.
• Understanding of Good Clinical Data Management Practices (GCDMP) and relevant regulatory requirements.
• Experience with clinical databases, data management systems, and electronic data capture (EDC).
• Ability to manage multiple projects simultaneously and meet deadlines proactively.
• Excellent written and verbal communication skills.
• Strong organizational and analytical skills with high attention to detail.
• Understanding of clinical data system design, development, validation, and system interoperability.
• Experience working effectively with external partners.
• Knowledge of database structures, programming languages, data standards (CDISC), and practices related to CRF design, database development, data handling, and reporting.
• Knowledge of SQL or SAS software.

Why AstraZeneca?

AstraZeneca has been recognized with numerous awards, including:

• GTAA Top Employer Award for 10 years.
• Top 100 Employers Award.
• Canada’s Most Admired Corporate Culture.

Learn more about working with us in Canada by exploring our .

Interested in joining our team? Apply today!

AstraZeneca is an equal opportunity employer committed to diversity and inclusion. We provide a workplace free from discrimination and are committed to accommodating individuals with disabilities. Accommodation can be requested in all aspects of the recruitment, assessment, and selection process by emailing .